Roberto Giovannoni
Position
Academic Researcher in Pathology at the School of Medicine, University of Milano-Bicocca.
Research activities and skills
Research activities and skills
- Genetic engineering tools for in vitro and in vivo modelling
- Validation of molecular and diagnostic markers in cancer biology
- Study of adenosine and extracellular nucleotide metabolism in the molecular mechanisms of cytoprotection against inflammatory stimuli
- Innovative therapeutic approaches for inflammatory diseases based on plant biotechnologies
Most Relevant Publication
Chisci E, De Giorgi M, Zanfrini E, Testasecca A, Brambilla E, Cinti A, Farina L, Kutryb-Zajac B, Bugarin C, Villa C, Grassilli E, Combi R, Gaipa G, Cerrito MG, Rivolta I, Smolenski RT, Lavitrano M, Giovannoni R. Simultaneous overexpression of human E5NT and ENTPD1 protects porcine endothelial cells against H2O2-induced oxidative stress and cytotoxicity in vitro. Free Radic Biol Med. 2017;108:320-333
Romano G, Santi L, Bianco MR, Giuffrè MR, Pettinato M, Bugarin C, Garanzini C, Savarese L, Leoni S, Cerrito MG, Leone BE, Gaipa G, Grassilli E, Papa M, Lavitrano M, Giovannoni R. The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells. Oncotarget. 2016
Giovannoni R, Villanueva A. Circulating tumor cells and cholangiocarcinoma. Hepatology. 2016;63(1):23-5
Grassilli E, Pisano F, Cialdella A, Bonomo S, Missaglia C, Cerrito MG, Masiero L, Ianzano L, Giordano F, Cicirelli V, Narloch R, D'Amato F, Noli B, Ferri GL, Leone BE, Stanta G, Bonin S, Helin K, Giovannoni R, Lavitrano M. A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation. Oncogene. 2016 Aug 18;35(33):4368-78.
Salerno D, Beretta GL, Zanchetta G, Brioschi S, Cristofalo M, Missana N, Nardo L, Cassina V, Tempestini A, Giovannoni R, Cerrito MG, Zaffaroni N, Bellini T, Mantegazza F. Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements. Biophys J. 2016;110(10):2151-2161
Cinti A, De Giorgi M, Chisci E, Arena C, Galimberti G, Farina L, Bugarin C, Rivolta I, Gaipa G, Smolenski RT, Cerrito MG, Lavitrano M, Giovannoni R. Simultaneous overexpression of functional human HO-1, E5NT and ENTPD1 protects murine fibroblasts against TNF-α-induced injury in vitro. PLoS ONE. 2015. 10(10):e0141933
De Giorgi M, Cinti A, Pelikant-Malecka I, Chisci E, Lavitrano M, Giovannoni R, Smolenski RT. Co-expression of functional human Heme Oxygenase 1, Ecto-5'-Nucleotidase and ecto-nucleoside triphosphate diphosphohydrolase-1 by "self-cleaving" 2A peptide system. Plasmid. 2015;79:22-9
Busnelli M, Manzini S, Froio A, Vargiolu A, Cerrito MG, Smolenski RT, Giunti M, Cinti A, Zannoni A, Leone BE, Forni M, Bacci ML, Biasi GM, Giovannoni R, Lavitrano M. Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury - Rescue by High-Dose Statin Treatment. PLoS One. 2013;8(11):e80588.