Maria Elena Regonesi
Position
Assistant professor in Biochemistry at the Department of Biotechnology and Biosciences, University Milano-Bicocca
Research activities and skills
Study of metabolic pathway of active metabolites and strategy to enhance their productions and activities. Analysis of the effect of single molecule or complex (i.e. plant extract) on neuro-system to evaluate the relationships among food and neurodegenerative disease preventions.
Most Relevant Publication
Bonanomi, M., Visentin, C., Natalello, A., Spinelli, M., Vanoni, M., Airoldi, C., Regonesi, ME., Tortora P. (2015) How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode. Chemistry. Nov 5.
Bonanomi, M., Visentin, C., Invernizzi, G., Tortora, P., Regonesi, ME. (2015) The Toxic Effects of Pathogenic Ataxin-3 Variants in a Yeast Cellular Model. PLoS One. 10:e0129727.
Sironi, E., Colombo, L., Lompo, A., Messa, M., Bonanomi, M., Regonesi, M.E., Salmona, M., Airoldi, C. (2014) Natural Compounds against Neurodegenerative Diseases: Molecular Characterization of the Interaction of Catechins from Green Tea with Aβ1-42, PrP106-126, and Ataxin-3 Oligomers. Chemistry. 20, 13793-800.
Bonanomi, M., Natalello, A., Visentin, C., Pastori, V., Penco, A., Cornelli, G., Malabarba, M.G., Colombo, G., Doglia, S.M., Relini, A., Regonesi, M.E., Tortora, P. (2014) Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model. Hum. Mol. Genet. 23, 6542-52.