Elena Rita Lonati
Position
Research fellow.
Research activities and skills
Evaluation of the anti-oxidant and anti-inflammatory power of the selected natural extracts in in vitro cellular systems of both intestinal barrier and blood-brain barrier, in order to understand its potential use in food formulations. Evaluation of molecular pathways related to neurodegenerative diseases.
Most Relevant Publication
1)*LonatiE, *Corsetto PA, Montorfano G, ZavaS, Carrozzini T, Brambilla A, Botto L, PalestiniP, Rizzo AM, BulbarelliA. LipidReshapingand LipophagyAre Inducedin a ModeledIschemia-ReperfusionInjuryof Blood Brain Barrier.IntJ MolSci. 2019 Jul31;20(15). pii: E3752. doi: 10.3390/ijms20153752.
2)*FarinaF, *Lonati E, Milani C, Massimino L, Ballarini E, Donzelli E, Crippa L, MarmiroliP, Botto L, Corsetto PA, SanciniG, BulbarelliA, PalestiniP. In Vivo Comparative Studyon Acute and Sub-acute BiologicalEffectsInducedby UltrafineParticlesof DifferentAnthropogenicSourcesin BALB/c Mice. IntJ MolSci. 2019 Jun8;20(11). pii: E2805. doi: 10.3390/ijms20112805.
3)LonatiE, Sala G, TresoldiV, Coco S, Salerno D, Milani C, LosurdoM, Farina F, Botto L, Ferrarese C, PalestiniP, BulbarelliA. IschemicConditionsAffectReroutingof Tau ProteinLevels:Evidencesfor Alterationin Tau Processing and Secretionin HippocampalNeurons. J MolNeurosci. 2018 Dec;66(4):604-616. doi: 10.1007/s12031-018-1199-7.
4)MilaniC, Corsetto PA, Farina F, Botto L, Lonati E, Massimino L, Rizzo AM, BulbarelliA, PalestiniP. Earlyevidenceof stress in immortalizedneuronsexposedto diesel particles: the roleof lipidreshapingbehindoxidativestress and inflammation.Toxicology. 2018 Nov1;409:63-72. doi: 10.1016/j.tox.2018.07.017. Epub2018 Jul25.
5)*FarinaF, *Lonati E, Brambilla A, Dal Magro R, Milani C, Botto L, SanciniG, PalestiniP, BulbarelliA. (2017) Diesel exhaustparticles(DEP) pre-exposurecontributesto the anti-oxidantresponseimpairmentin hCMEC/D3duringpost-oxygenand glucosedeprivationdamage.ToxicolLett. 274:1-7. doi: 10.1016/j.toxlet.2017.04.003.