Michela Clerici


Associate professor in Genetics at the Department of Biotechnology and Biosciences, University of Milano Bicocca.

Research activities and skills

Cellular response to DNA damage, in particular DNA repair mechanisms and coordination between repair and cell cycle progression in response to environmental stress. Yeast is used as a model system to investigate molecular mechanism that preserve genome integrity.

Most Relevant Publication

Colombo CV, Trovesi C, Menin L, Longhese MP, Clerici M. The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1. (2017) Nucleic Acids Res. 45, 6530-6545.

Cassani C, Gobbini E, Wang W, Niu H, Clerici M, Sung P, Longhese MP. Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks. (2016) PLoS Biol. 14:e1002387.

Manfrini N, Clerici M, Wery M, Colombo CV, Descrimes M, Morillon A, d'Adda di Fagagna F, Longhese MP. Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae. (2015) Elife, 4. doi: 10.7554/eLife.08942.

Clerici M, Trovesi C, Galbiati A, Lucchini G, Longhese MP. Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends. (2014) EMBO J. 33:198-216.

Bonetti D, Anbalagan S, Lucchini G, Clerici M, Longhese MP. Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends. (2013) EMBO J. 32:275-89.

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